Primary pulmonary meningioma: A case report and review of the literature

Table 1 Patient characteristics

No.	Ref.	Age (Gender)	Symptom	Size (cm)	Histology	Follow-up
1	Kemnitz et al[3]	59 (F)	Weakness, loss ofappetite, weight loss	4.0	B	30
2	Chumas et al[14]	58 (F)	None	4.0	B	12
3	Zhang et al[15]	58 (F)	None	2.5	B	18
4	Kodama et al[16]	53 (M)	None	2.6	B	84
5	Drlicek et al[17]	41 (M)	None	2.5	B	72
6		62 (F)	None	6.0	B	72
7	Flynn et al[18]	63 (F)	Coughing	3.0	B	44
8		74 (F)	None	1.7	B	37
9	Maiorana et al[19]	68 (M)	None	1.8	B	24
10	Kaleem et al[20]	45 (F)	None	1.2	B	10
11	Lockett et al[21]	65 (M)	None	0.8	B	5
12	Ueno et al[22]	61 (F)	None	0.4-1.5	B	36
13	de Perrot et al[5]	57 (F)	None	0.9	B	30
14	Prayson et al[23]	51 (M)	None	6.5	M	10
15	Spinelli et al[24]	71 (F)	Bronchitis	1.5	B	96
16	Falleni et al[7]	59 (M)	None	2.5	B	30
17	Cesario et al[25]	56 (M)	None	2.0	B	72
18	CURA et al[26]	58 (F)	None	2.0	B	N
19	Comin et al[27]	33 (M)	Hemoptysis and thoracic pain	2.0	B	47
20	Rowsell et al[28]	51 (M)	None	4.0	B	8
21	Picquet et al[9]	54 (F)	None	1.4	B	6
22	Kaneda et al[29]	59 (F)	None	1.4	B	14
23	van der Meij et al[30]	40 (F)	Dyspnea, coughing dysphagia	5.0	M	40
24	Meirelles et al[31]	48 (M)	None	1.5	B	N
25	Incarbone et al[32]	24 (M)	Hemoptysis	2.4	B	42
26	Izumi et al[33]	18 (F)	Hemoptysis on exertion	3.3	B	15
27	Weber et al[4]	108 (F)	Asthenia, lack of appetite, loss of weight and anxiety	15.0	M	N
28	Lepanto et al[10]	60 (F)	None	1.6	B	12
29	Kim et al[34]	61 (F)	Chest pain	2.5	B	84
30	Jiang et al[35]	63 (F)	None	3.5	B	N
31	Juan et al[11]	55 (M)	None	4.5	B	6
32	Oide et al[36]	44 (M)	None	2.0	B	N
33	Huang et al[37]	44 (F)	Chest pain	2.5	B	6
34	Žulpaitė et al[38]	43 (F)	None	4.5	M	24
35	Hong et al[39]	54 (M)	Cough and sputum	1.6	B	24
36	Luo et al[40]	65 (F)	Cough	3.5	B	N
37	Xu et al[41]	65 (F)	Chest pain and tightness	0.7	B	N
38	Ohashi et al[42]	60 (F)	None	2.0	B	36
39	Bae et al[43]	43 (F)	None	1.9	B	26
40	Cimini et al[13]	80 (M)	None	1.4	B	N
41		80 (M)	None	1.2	M	N
42	Wang et al[44]	64 (F)	None	3.4 (cystic nodules 0.8-2)	B	N
43	Fujikawa et al[12]	62 (F)	None	0.8	B	20
45	Han et al[6]	64 (F)	None	0.6	B	28
44		75 (F)	None	0.6	B	2
46	Gürçay et al[45]	55 (F)	Cough	2.0	B	N
47	Jiang et al[8]	70 (M)	None	1.5	B	N
48	Bas et al[46]	57 (M)	Cough	1.0	B	N
49	Oh et al[47]	54 (M)	None	0.5-1.3	B	24
50	Present report	46 (F)	None	6.9	B	3

F: Female; M: Male; None: No symptoms; B: Benign; M: Malignant; N: Not reported.

Table 2 Radiological characteristics

No.	Ref.	Location	CT feature	Enhancement feature	PET/CT
1	Kemnitz et al[3]	RL-P	Well-circumscribed	N	N
2	Chumas et al[14]	RL-P	Well-circumscribed	N	N
3	Zhang et al[15]	LU-P	Well-circumscribed	N	N
4	Kodama et al[16]	LU-P	N	N	N
5	Drlicek et al[17]	LL-N	Well-circumscribed	N	N
6		LL-N	N	N	N
7	Flynn et al[18]	LU-C	Well-circumscribed	N	N
8		LL-P	Well-circumscribed	N	N
9	Maiorana et al[19]	N-P	Well-circumscribed	N	N
10	Kaleem et al[20]	LL-P	Well-circumscribed	N	N
11	Lockett et al[21]	LL-P	Well-circumscribed	N	N
12	Ueno et al[22]	Bil-N	N	N	N
13	de Perrot et al[5]	RL-P	Well-circumscribed	N	N
14	Prayson et al[23]	RU-P	Smooth margins and focal necrosis	N	N
15	Spinelli et al[24]	N-P	Lobulated margins	N	N
16	Falleni et al[7]	LU-P	Well-circumscribed	N	N
17	Cesario et al[25]	LU-P	Well-circumscribed	N	N
18	CURA et al[26]	RU-C	Well-circumscribed	Enhancement	High uptake (no value)
19	Comin et al[27]	LU-P	N	N	N
20	Rowsell et al[28]	RL-C	N	N	N
21	Picquet et al[9]	LL-P	Well-circumscribed	N	N
22	Kaneda et al[29]	N-P	Well-circumscribed	N	N
23	van der Meij et al[30]	RH-C	N	N	N
24	Meirelles et al[31]	RL-C	Lobulated margins	N	High uptake (12.9)
25	Incarbone et al[32]	RU-P	Lobulated margins	N	High uptake (10.14)
26	Izumi et al[33]	LU-C	Well-circumscribed	N	N
27	Weber et al[4]	RL-C	N	N	N
28	Lepanto et al[10]	LL-P	N	N	Low uptake (1.2)
29	Kim et al[34]	RU-P	Well-circumscribed	Homogeneous enhancement enhancement	N
30	Jiang et al[35]	LU-P	Well-circumscribed	N	N
31	Juan et al[11]	LU-P	Ground-glass opacity	N	N
32	Oide et al[36]	LU-P	Well-circumscribed	N	N
33	Huang et al[37]	RL-P	Calcifications, mild peripheral lobulation	Mild enhancement	N
34	Žulpaitė et al[38]	LU-P	N	Homogeneous enhancement	N
35	Hong et al[39]	LU-P	Well-circumscribed	Heterogeneous enhancement	N
36	Luo et al[40]	RL-P	Heterogeneous lobulated	N	N
37	Xu et al[41]	RL-P	Well-circumscribed	N	N
38	Ohashi et al[42]	RL-P	N	N	N
39	Bae et al[43]	RL-C	Oval-shaped	Well-enhancement	Mildly high uptake (2.48)
40	Cimini et al[13]	RU-P	N	No significant enhancement	High uptake (4.63)
41		LU-N	N	Enhancement	Mildly high uptake (2.46)
42	Wang et al[44]	RL-N	Multiple thin-, smooth-walled cysts or cystic nodules with solid component	Mild enhancement	N
43	Fujikawa et al[12]	LL-P	Well-circumscribed	N	N
45	Han et al[6]	RL-P	Burrs on the edges	N	N
44		RL-P	Burrs on the edges	N	N
46	Gürçay et al[45]	RU-P	Peripheral ground-glass	N	Low uptake (1.89)
47	Jiang et al[8]	RL-P	Well-circumscribed	Mild centripetal enhancement	Low uptake (0.6)
48	Bas et al[46]	LL-P	Well-circumscribed	N	Low uptake (no value)
49	Oh et al[47]	scattered	Well-circumscribed	N	Mildly high uptake (3.1)
50	Present report	LL-C	Well-circumscribed	Mild homogeneous enhancement	High uptake (4.4)

RL: Right lower lobe; RU: Right upper lobe; LL: Left lower lobe; LU: Left upper lobe; P: Peripheral or subpleural; C: Centrilobar; N: Not reported.

Table 3 Clinical and imaging characteristics of primary pulmonary meningioma patients

Variables		Number	Ratio (%)
Gender (n = 50)	Female	31	62.0
	Male	19	38.0
Age (n = 50)	≤ 40 yr	4	8.0
	40–60 yr	26	52.0
	≥ 60 yr	20	40.0
Symptoms (n = 50)	No	35	70.0
	Yes	15	30.0
Size (n = 50)	≤ 3 cm	37	74.0
	> 3 cm	13	26.0
Histology (n = 50)	Benign	45	90.0
	Malignant	5	10.0
Site (n = 47)	RL	15	31.9
	RU	6	12.8
	LL	10	21.3
	LU	13	27.7
	Other	3	6.4
Location (n = 45)	Peripheral	36	80.0
	Centrilobar	9	20.0
Main CT features (n = 38)	Well-circumscribed	27	71.1
	Lobulated	5	13.2
	Burrs	2	5.3
	Ground-glass density	2	5.3
	Calcification	2	5.3
PET/CT (n = 12)	High uptake	8	66.7
	Low uptake	4	33.3

RL: Right lower lobe; RU: Right upper lobe; LL: Left lower lobe; LU: Left upper lobe.