Age, alcohol, sex, and metabolic factors as risk factors for colonic diverticulosis

Table 1 Baseline characteristics of the subjects

Parameter	Diverticulosis (+), 449	Diverticulosis (-), 5731	P value
Mean Age	50.57 ± 10.116	47.92 ± 10.533	< 0.001
Age < 40	60	1203
60 > Age ≥ 40	300	3669
Age > 60	89	859	< 0.001
Male gender	382 (85.1%)	3622 (63.2%)	< 0.001
Mean BMI	25.03 ± 3.226	23.84 ± 3.131	< 0.001
Obesity (BMI ≥ 28)	77 (17.1%)	528 (9.2%)	< 0.001
Smoker	190 (42.3%)	1601 (27.9%)	< 0.001
Alcohol	185 (41.2%)	2158 (37.7%)	< 0.001
Systolic blood pressure, mmHg	132.07 ± 18.608	125.19 ± 17.995	< 0.001
Diastolic blood pressure, mmHg	78.82 ± 12.27	74.14 ± 12.278	< 0.001
Hypertension, (BP ≥ 130/80mmHg )	183 (40.8%)	1447 (25.2%)	< 0.001
TG, mmol/L,	2.38 ± 2.277	1.80 ± 1.549	< 0.001
Hypertriglyceridemia, (TG ≥ 2.3 mmol/L)	166(37.0%)	1272(22.2%)	< 0.001
TC, mmol/L	5.49 ± 1.122	5.32 ± 1.090	0.001
Hypercholesteremia, (TC ≥ 6.2 mmol/L)	116(25.8%)	1087(19.0%)	0.001
FBG, mmol/L	5.08 ± 1.270	4.88 ± 1.229	0.001
Hyperglycemia, (FBG ≥ 6.1 mmol/L)	56(12.5%)	421(73.5%)	< 0.001
UA, umol/L	388.73 ± 90.508	344.57 ± 87.70	< 0.001
Hyperuricemia, (UA ≥ 420umol/L)	160(35.6%)	1074(18.7%)	< 0.001

Continuous variables are reported as mean ± SD; categorical variables are reported as n (%). BMI: Body mass index; BP: Blood pressure; TC: Total cholesterol; TG: Triglyceride; FBG: Fasting blood glucose; UA: Uric acid.

Table 2 Logistic regression analysis for the risk factors of diverticulosis

	Adjusted OR	P value	95%CI
Age
< 40	1	1	1
60 > Age ≥ 40	1.489	0.007	1.112-1.993
Age ≥ 60	2.149	< 0.001	1.511-3.057
Male gender	1.878	< 0.001	1.373-2.568
Obesity	1.446	0.008	1.100-1.902
Smoker	1.175	0.154	0.941-1.466
Alcohol	1.518	< 0.001	1.213-1.901
Hypertension	1.454	< 0.001	1.181-1.789
Hypercholesteremia	1.244	0.064	0.988-1.567
Hypertriglyceridemia	1.287	0.025	1.032-1.607
Hyperglycemia	1.281	0.121	0.937-1.750
Hyperuricemia	1.570	< 0.001	1.257-1.961

Logistic regression analysis adjusted for age, male sex, body mass index, smoking habit, alcohol consumption, hypertension, hypercholesteremia, hypertriglyceridemia, hyperglycemia, hyperuricemia.