Copyright ©The Author(s) 2021.
World J Clin Cases. Dec 6, 2021; 9(34): 10400-10417
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10400
Figure 1
Figure 1 The milestones in circRNA research from its discovery in 1976 to present. circRNA: Circular RNA.
Figure 2
Figure 2  Four mechanisms of circular RNA formation including exonic circular RNA, intronic circular RNA, exon-intron circular RNA, intergenic circular RNA.
Figure 3
Figure 3  Circular RNAs have a regulatory effect on gastrointestinal tumors via signaling molecules, and have been shown to influence drug resistance in gastric, liver, intestinal, esophageal, and pancreatic cancer.