Individualized treatment of breast cancer with chronic renal failure: A case report and review of literature

Figure 1 Breast ultrasound results of the patient obtained during preoperative neoadjuvant treatment. A and B: September 15, 2020. M: Left breast mass (37 mm × 31 mm × 30 mm) (A) and LN: Left axillary lymph node (the largest node was 16 mm × 10 mm × 10 mm) (B); C and D: December 21, 2020. M-LBR: Left breast mass (16 mm × 13 mm ×12 mm) (C) and LN: Left axillary lymph node (the largest node was 13 mm × 8 mm × 6 mm) (D); E and F: January 26, 2021. MLBR: Left breast mass (12 mm × 9 mm × 8 mm) (E) and LN: Left axillary lymph node (the largest node was 10 mm × 6 mm × 5 mm) (F).

Figure 2 Pathological results of left breast tumor and left axillary lymph node biopsies. A: Hematoxylin and eosin-stained sections revealed that the tumor cells grew in a solid and patchy infiltrating manner (original magnification: 200 ×); B: Hematoxylin and eosin-stained sections revealed that the left axillary lymph node was metastatic carcinoma, which was consistent with the breast source (original magnification: 200 ×); C: C-erBb2 (2+) was uncertain in neoplastic cells by immunohistochemical analysis (original magnification: 200 ×); D and E: Estrogen receptor and progesterone receptor were negative in neoplastic cells by immunohistochemical analysis (original magnification: 200 ×); F: Ki-67 was expressed in the nuclei of approximately 40% of tumor cells (original magnification: 200 ×); G: HER-2 was amplified by fluorescence in situ hybridization (original magnification: 200 ×).

Figure 3 Magnetic resonance imaging of the patient obtained during preoperative neoadjuvant treatment. A: September 28, 2020: Left breast mass (37 mm × 31 mm × 34 mm); B: November 12, 2020: Left breast mass (22 mm × 21 mm × 25 mm); C: December 21, 2020: Left breast mass (16 mm × 13 mm × 12 mm); D: January 27, 2021: Left breast mass (12 mm × 9 mm × 8 mm). Red arrows indicate localization of masses.