Validation of diagnostic strategies of autoimmune atrophic gastritis: A case report

Figure 1 Endoscopic findings. Endoscopy shows normal mucosa in the gastric antrum (A); and atrophic mucosa in the gastric fundus and body (B and C). Narrow band imaging shows enlarged tubular structures without regular arrangement of collecting venules and pseudopyloric changes in the gastric fundus and body (D).

Figure 2 Pathological findings. Pathology revealed decreased density of glands and lymphocyte infiltration in both the epithelium and lamina propria of the gastric fundus and body (A1 and B1). However, the mucosa in the gastric antrum did not show atrophic changes (C1). Immunohistochemical results show negative hydrogen-potassium adenosine triphosphatase antibody staining and positive chromogranin A staining in most of the gastric mucosa (A2, B2, C2, A4, B4 and C4). Pepsinogen I staining is positive in a small number of glands in the gastric fundus and body (A3, B3 and C3).