Development and validation of a prognostic nomogram model for Chinese patients with primary small cell carcinoma of the esophagus

Figure 1 Survival analysis in the primary cohort. A: Univariate analysis in the primary cohort; B: Multivariate analysis in the primary cohort. T: Tumor invasion depth; N: Number of positive lymph nodes; CD56: Neuronal cell adhesion molecule 56; CgA: Chromogranin A; Syn: Synaptophysin.

Figure 2 Nomogram model for predicting the 1-, 3-, and 5-year overall survival in primary small cell carcinoma of the esophagus patients. N: Number of positive lymph nodes; T: Tumor invasion depth; CD56: Neuronal cell adhesion molecule 56; CgA: Chromogranin A.

Figure 3 Calibration curves for predicting overall survival at (A) 1 year, (B) 3 years, and (C) 5 years in the primary cohort and at (D) 1 year, (E) 3 years, and (F) 5 years in the validation cohort. OS: Overall survival.

Figure 4 Decision curve analysis for the 18-mo survival predictions in primary small cell carcinoma of the esophagus patients. TNM: Tumor node metastasis.

Figure 5 Kaplan–Meier curves for all three groups based on the nomogram prediction. A: Kaplan–Meier curves for all three groups in the primary cohort. B: Kaplan–Meier curves for all three groups in the validation cohort.

Figure 6 Distribution of the nomogram predicted 5-year survival rate according to 7^th edition tumor node metastasis stages. A: Distribution in the primary cohort; B: Distribution in the validation cohort. TNM: Tumor node metastasis.