Copyright
©The Author(s) 2021.
World J Clin Cases. Sep 16, 2021; 9(26): 7653-7670
Published online Sep 16, 2021. doi: 10.12998/wjcc.v9.i26.7653
Published online Sep 16, 2021. doi: 10.12998/wjcc.v9.i26.7653
Figure 1 Potential targets of action of Jianpi Qingchang Huashi Recipe in the treatment of ulcerative colitis.
C-T: Active component targets; D-T: Ulcerative colitis-related targets.
Figure 2 The visual network of "traditional Chinese medicine drugs-Active Components-Targets-Diseases".
The circles represent the active component, the diamonds represent traditional Chinese medicine drugs, the arrows represent the disease targets, and the hexagons represent the diseases.
Figure 3 Diagram of protein–protein interactions.
Figure 4 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis of the potential targets of action of Jianpi Qingchang Huashi Recipe in the treatment of ulcerative colitis.
BP: Biological process; CC: Cellular component; KEGG: Kyoto Encyclopedia of Genes and Genomes; MF: Molecular function.
Figure 5 Molecular docking patterns between AKT1, TP53, MAPK1 and MAPK3 and quercetin, luteolin, naringenin and kaempferol.
- Citation: Zheng L, Wen XL, Dai YC. Mechanism of Jianpi Qingchang Huashi Recipe in treating ulcerative colitis: A study based on network pharmacology and molecular docking. World J Clin Cases 2021; 9(26): 7653-7670
- URL: https://www.wjgnet.com/2307-8960/full/v9/i26/7653.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i26.7653