Cytomegalovirus colitis induced segmental colonic hypoganglionosis in an immunocompetent patient: A case report

Figure 1 Abdominal X-ray and computed tomography images. A and B: Abdominal X-ray and computed tomography (CT) scan at initial admission showed fecal impaction and diffuse dilatation of the entire colon; C and D: Abdominal X-ray and CT scan 8 mo after initial admission showed aggravation of fecal impaction and bowel dilatation involving both the ascending and the descending colon with edematous colonic wall thickening in the sigmoid colon.

Figure 2 Sigmoidoscopic images. A: Initial sigmoidoscopy showed geographic ulcerative lesions with extremely friable mucosa in the sigmoid colon, which could bleed easily when touch; B: 3 mo after intravenous ganciclovir administration, ulcerative lesions had improved on sigmoidoscopy.

Figure 3 Histopathological findings. A and B: Reduced number of ganglion cells in the sigmoid colon; C and D: Number of ganglion cells was relatively maintained in the proximal colon. Arrow: Normal ganglion cell (D).