Anderson-Fabry disease presenting with atrial fibrillation as earlier sign in a young patient: A case report

Figure 1 The patient’s electrocardiogram before and after rhythm conversion. A: The electrocardiogram (ECG) shows atrial fibrillation with left ventricular hypertrophy upon admission; B: After spontaneous rhythm conversion to normal sinus rhythm, the surface ECG reveals a short PR interval (120 ms) and an unmeasurable P_end-Q interval.

Figure 2 Echocardiographic images in the patient with Fabry disease. A: The apical 4-chambers view reveals brighten endocardium, slightly thickened mitral valves, and thickened left atrial wall; B: M-mode shows thickened left ventricular walls (up to 14 mm).

Figure 3 Cutaneous manifestations in the patient. Angiokeratomas (small, numerous, and dark red/purple spots) on both hands and flank are observed. A: Hands; B: Flank.