Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review

Figure 1 Computed tomography of the abdomen showing the hypodense splenic lesion on non-contrast and contrast-enhanced images. A: Non-contrast phase of computed tomography showed a hypodense solid lesion, 5.9 cm × 5.1 cm, located at the upper pole of the spleen; B: Contrast-enhanced image showed a mild progressive enhancement of the lesion.

Figure 2 Cut section of the spleen showing well encapsulated splenic lesion, off-white and dull-red in color, and firm in consistency.

Figure 3 Microscopic appearance of the splenic lesion showing multiple rounded hemangiomatous nodules surrounded by fibrosclerotic stroma (hematoxylin and eosin, 100 ×).

Figure 4 Immunohistochemical analysis showed positive staining of the splenic tumor tissues for the following stains. A: CD31, B: CD34, C: CD68, D: Smooth-muscle actin.