Li SX, Fan YH, Wu H, Lv GY. Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review. World J Clin Cases 2021; 9(1): 211-217 [PMID: 33511187 DOI: 10.12998/wjcc.v9.i1.211]
Corresponding Author of This Article
Guo-Yue Lv, PhD, Professor, Department of Hepatobiliary and Pancreatic Surgery, First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. lgy08@sina.com
Research Domain of This Article
Biochemical Research Methods
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 6, 2021; 9(1): 211-217 Published online Jan 6, 2021. doi: 10.12998/wjcc.v9.i1.211
Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review
Shu-Xuan Li, Ye-Hui Fan, Hao Wu, Guo-Yue Lv
Shu-Xuan Li, Hao Wu, Guo-Yue Lv, Department of Hepatobiliary and Pancreatic Surgery, First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Ye-Hui Fan, Department of The First Operation Room, First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Li SX and Fan YH contributed equally to this work; Li SX wrote the original draft of the manuscript; Fan YH was responsible for the methodology and data curation; Wu H performed the analyses and interpretation of the imaging findings; Lv GY was responsible for the revision and editing of the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: The patient provided informed written consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Yue Lv, PhD, Professor, Department of Hepatobiliary and Pancreatic Surgery, First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. lgy08@sina.com
Received: July 15, 2020 Peer-review started: July 15, 2020 First decision: August 8, 2020 Revised: August 17, 2020 Accepted: November 12, 2020 Article in press: November 12, 2020 Published online: January 6, 2021 Processing time: 170 Days and 4.1 Hours
Abstract
BACKGROUND
Sclerosing angiomatoid nodular transformation (SANT) is a rare disease of the spleen. It has unique pathological features and mimics splenic tumor on radiological imaging.
CASE SUMMARY
A 47-year-old woman was incidentally found to have a splenic mass on abdominal ultrasound. She had a 10-cm postoperative scar in the lower abdomen due to previous cesarean sections. The patient had a past history of anemia of unknown etiology for 20 years. The patient underwent laparoscopic splenectomy. The postoperative course was uneventful, with a hospital stay of 7 d. The histopathological examination of the spleen revealed SANT. At the 6-mo follow-up, the patient remained disease-free.
CONCLUSION
SANT is a rare benign disease mimicking a malignant tumor. A definitive diagnosis can be made only on histopathology.
Core Tip: We report the case of a 47-year-old lady with long-standing anemia with an incidentally detected splenic mass of 5.9 cm × 5.1 cm that appeared malignant on computed tomography. The patient underwent laparoscopic splenectomy. Histopathological examination of the spleen revealed sclerosing angiomatoid nodular transformation (SANT). SANT is a rare benign disease of the spleen that mimics malignancy on radiological imaging. Preoperative diagnosis of SANT is difficult. SANT should be included in the differential diagnosis when treating patients with a splenic mass.
