Initial experience with stereotactic body radiotherapy for intrahepatic hepatocellular carcinoma recurrence after liver transplantation

Figure 1 Outcomes of stereotactic body radiotherapy. A: Best local response according the Modified response Evaluation Criteria for Solid Tumours criteria; B: Pattern of disease progression after stereotactic body radiotherapy.

Figure 2 Kaplan Meier curve denoting disease progression-free survival after stereotactic body radiotherapy. SBRT: Stereotactic body radiation therapy.

Figure 3 Representative images of patient No. 2. A: First recurrence with S7 tumour invading inferior vena cava (arrow: Inferior vena cava tumour thrombus; arrowhead: stomach); B: Stereotactic planning to minimize collateral radiation to the normal liver and stomach (arrowhead); C: S7 and S8 recurrent tumours showed partial response after stereotactic body radiotherapy. Inferior vena cava was re-cannulated (arrow); D: Multifocal intrahepatic recurrences in the graft (arrows).

Figure 4 Patient No. 4 had recurrent hepatocellular carcinoma over S3 (arrow) close to stomach (arrowhead). He developed gastric ulcer necessitating proton pump inhibitor therapy.

Figure 5 Liver function parameters after stereotactic body radiation therapy. A: Aspartate aminotransferase; B: Alanine aminotransferase; C: Bilirubin.