Evaluation of clinical significance of claudin 7 and construction of prognostic grading system for stage II colorectal cancer

Figure 1 Immunochemical staining of claudin 7. A: Immunochemical staining of claudin 7 in normal colorectal tissue; B: Immunochemical staining of claudin 7 in cancer tissue.

Figure 2 Comparison of claudin 7 expression in colorectal cancer tissues and normal tissues (P < 0. 001). N/W: Negative/weak expression; M: Moderate expression; S: Strong expression.

Figure 3 Kaplan-Meier curves for disease-free survival. A: Kaplan-Meier survival curves for patients with high and low claudin 7 expression (P = 0.011, log-rank test); B: Kaplan-Meier survival curves for patients with or without perineural invasion (P = 0.002, log-rank test); C: Kaplan-Meier survival curves for patients with different prognostic grades (P < 0.001, log-rank test).