Brain abscess from oral microbiota approached by metagenomic next-generation sequencing: A case report and review of literature

Figure 1 The patient's brain magnetic resonance imaging results before treatment and follow-up. A and E: Long T1-weighted imaging signal in left cerebellar hemisphere before treatment; B and F: Long T2-weighted imaging signal in left cerebellar hemisphere in follow-up; C: High T2-fluid-attenuated inversion recovery signal in left cerebellar hemisphere before treatment; D: Enhancement showing a multiventricular ring-like enhancement in left cerebellar hemisphere before treatment; G: Slightly high T2-FLAIR signal in left cerebellar hemisphere in follow-up; H: Enhancement showing a ring enhancement in left cerebellar hemisphere in follow-up. MRI: Magnetic resonance imaging; T1WI: T1-weighted imaging; T2WI: T2-weighted imaging; FLAIR: Fluid-attenuated inversion recovery.

Figure 2 Histopathological analysis and immunohistochemical examination of the extracted specimen. A: Hematoxylin and eosin staining (× 40); B: Immunohistochemical staining for showing CD3 positive staining (× 200); C: CD4 positive staining (× 100); D: CD20 positive staining (× 100); E: CD56 positive staining (× 400); F: CD68 positive staining (× 400); G: CD138 positive staining (× 400); H: MPO positive staining (× 400); I: PAS negative staining (× 100).