Transforming growth factor-β1 and vascular endothelial growth factor levels in senile acute myeloid leukemia and correlation with prognosis

doi:10.12998/wjcc.v12.i20.4121

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Jul 16, 2024 (publication date) through Jun 30, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jul 16, 2024; 12(20): 4121-4129
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4121

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Figure 1 Expression levels of vascular endothelial growth factor and transforming growth factor-β1. A: Expression levels of vascular endothelial growth factor; B: Expression levels of transforming growth factor-β1. AML: Acute myeloid leukemia; VEGF: Vascular endothelial growth factor; TGF-β1: Transforming growth factor-β1.

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Figure 2 Expression levels of vascular endothelial growth factor and transforming growth factor-β1 in patients with acute myeloid leukemia with different treatment responses and healthy controls. A: Expression levels of vascular endothelial growth factor; B: Expression levels of transforming growth factor-β1. AML: Acute myeloid leukemia; VEGF: Vascular endothelial growth factor; TGF-β1: Transforming growth factor-β1; CR: Complete response; PR: Partial response; NR: No response.

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Figure 3 Correlation between disease-free or overall survival rate and transforming growth factor-β1 or vascular endothelial growth factor expression analyzed using the Kaplan-Meier survival curve. A: Correlation between disease-free survival (DFS) rate and vascular endothelial growth factor (VEGF) expression analyzed using the Kaplan-Meier survival curve; B: Correlation between overall survival (OS) rate and VEGF expression analyzed using the Kaplan-Meier survival curve; C: Correlation between disease-free survival rate and transforming growth factor-β1 (TGF-β1) expression analyzed using the Kaplan-Meier survival curve; D: Correlation between OS rate and TGF-β1 expression analyzed using the Kaplan-Meier survival curve. AML: Acute myeloid leukemia; VEGF: Vascular endothelial growth factor; TGF-β1: Transforming growth factor-β1; DFS: Disease-free survival; OS: Overall survival.

Citation: Li W, Ma SY, Zhao HY. Transforming growth factor-β1 and vascular endothelial growth factor levels in senile acute myeloid leukemia and correlation with prognosis. World J Clin Cases 2024; 12(20): 4121-4129
URL: https://www.wjgnet.com/2307-8960/full/v12/i20/4121.htm
DOI: https://dx.doi.org/10.12998/wjcc.v12.i20.4121