Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2024; 12(20): 4121-4129
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4121
Transforming growth factor-β1 and vascular endothelial growth factor levels in senile acute myeloid leukemia and correlation with prognosis
Hui-Ying Zhao, Sheng-Yu Ma, Wan Li
Wan Li, Sheng-Yu Ma, Hui-Ying Zhao, Department of Hematology, Suzhou Hospital of Anhui Medical University, Suzhou 234000, Anhui Province, China
Author contributions: Wan L, Ma SY, and Zhao HY designed the study and were involved in the data acquisition and writing of this article; Wan L and Zhao HY contributed to the analysis of the manuscript; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Suzhou Hospital of Anhui Medical University (Approval No. C2024003).
Informed consent statement: All patients provided written informed consent for participation in the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Ying Zhao, Doctor, Associate Chief Physician, Department of Hematology, Suzhou Hospital of Anhui Medical University, No. 229 Bianhe Middle Road, Suzhou 234000, Anhui Province, China. 18155785701@163.com
Received: March 21, 2024
Revised: April 30, 2024
Accepted: May 17, 2024
Published online: July 16, 2024
Processing time: 101 Days and 15.3 Hours
Core Tip

Core Tip: At present, the prognosis and survival of acute myeloid leukemia (AML) remain unsatisfactory. In this paper, vascular endothelial growth factor and transforming growth factor-β1 expression in patients with AML was investigated to fully understand the molecular mechanism of angiogenesis and immunomodulation in AML to enhance treatment strategies for targeted therapy, thereby improving prognosis in patients with AML.