Diagnostic challenges and individualized treatment of cervical adenocarcinoma metastases to the breast: A case report

Figure 1 Laboratory examinations and diagnosis images. A: Cervical biopsy showing sheets of discohesive cells (40 × magnification); B: 40 × magnification breast biopsy with malignant cells infiltrating in single file staining positive for p16, Pax-8, ER, and human papillomavirus (by in situ hybridization). The breast biopsy was negative for typical breast-associated markers including mammaglobin and GCDFP.

Figure 2  Disease and treatment timeline.

Figure 3  Positron emission tomography/computed tomography coronal view at time of diagnosis before (left) and after (right) six cycles of carboplatin and paclitaxel with pembrolizumab.