Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 16, 2024; 12(2): 412-417
Published online Jan 16, 2024. doi: 10.12998/wjcc.v12.i2.412
Diagnostic challenges and individualized treatment of cervical adenocarcinoma metastases to the breast: A case report
Allison Akers, Susan Read, John Feldman, Casey Gooden, Diana P English
Allison Akers, Diana P English, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL 33606, United States
Susan Read, Department of Gynecologic Oncology, Sky Ridge Medical Center, Lone Tree, CO 80124, United States
John Feldman, Department of Radiology, University of South Florida, Tampa, FL 33606, United States
Casey Gooden, Department of Pathology, University of South Florida, Tampa, FL 33606, United States
Author contributions: Akers A, Read S, and English DP contributed to the investigation of this manuscript; Akers A, Read S, Feldman J, Gooden C, and English DP involved in the manuscript editing; Akers A and English DP wrote the manuscript; Read S and English DP took part in the conception of this manuscript; Feldman J provided the radiology images; Gooden C provided the pathology slides; English DP involved in care of patient.
Informed consent statement: The patient provided consent and the consent form is submitted.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Diana P English, MD, Associate Professor, Department of Obstetrics and Gynecology, University of South Florida, 2 Tampa General Circle, Tampa, FL 33606, United States. dianaenglish@usf.edu
Received: October 9, 2023
Peer-review started: October 9, 2023
First decision: November 13, 2023
Revised: November 27, 2023
Accepted: December 22, 2023
Article in press: December 22, 2023
Published online: January 16, 2024
Processing time: 94 Days and 4.9 Hours
Core Tip

Core Tip: Metastatic cervical cancer to the breast is rare with nonspecific clinical findings that can make diagnosis challenging. Clinical history, histology and immunohistochemical evaluation of the breast lesion, and comparison to the primary tumor can support the diagnosis of metastatic cervical cancer rather than a primary breast malignancy. Overall, the prognosis is poor, but immunotherapy can be considered in select patients and may result in good disease response.