Parathyroid carcinoma located in the thyroid gland: A case report

Figure 1 Colored ultrasound of the thyroid gland and cervical lymph nodes. A-C: The left lobe of the thyroid gland is enlarged, the right lobe is not large, and the echogenicity of glandular tissue is uneven. A mixed echogenic mass of about 38 mm × 30 mm was found in the left lobe of the thyroid, with a clear boundary and regular shape. Several strong echogenic spots of different sizes were observed inside, accompanied by acoustic shadow behind.

Figure 2 Parathyroid imaging (MIBI). A-C: A concentrated shadow of radioactivity in the left lobe of the thyroid.

Figure 3 Fine needle aspiration cytological smear of thyroid nodules. A-C: Patches of thyroid follicular epithelium with crowded cells were detected. Some cells showed intranuclear pseudoinclusions, and nuclear furrows were rare. The pathological case was considered papillary thyroid carcinoma.

Figure 4 Pathological findings. A: Fiber separation (10×); B: Capsular invasion (10×); C: Endovascular invasion (10×); D: Fatty infiltration (10×). E: Heterocyst (40×); F: Parathyroid hormone staining (40×); G: Ki67 staining (40×); H: Calcitonin staining (40×).