Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2024; 12(18): 3609-3614
Published online Jun 26, 2024. doi: 10.12998/wjcc.v12.i18.3609
Parathyroid carcinoma located in the thyroid gland: A case report
Shu-Yan Gui, Chang-Ning Zhang, Li Ling, Ruo-Xi Tang, Jing Yang
Shu-Yan Gui, Chang-Ning Zhang, Li Ling, Ruo-Xi Tang, Jing Yang, Department of Endocrinology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen 518052, Guangdong Province, China
Author contributions: Yang J and Gui SY reviewed the literature and contributed to manuscript drafting; Zhang CN analyzed and interpreted the imaging findings; Ling L reviewed the literature and drafted the manuscript; Tang RX were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed consent of the patient for publication, including personal data and pictures.
Conflict-of-interest statement: All the authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing Yang, Doctor, Chief Doctor, Department of Endocrinology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Taoyuan Road, Nanshan District, Shenzhen 518052, Guangdong Province, China. yangjing9803@hotmail.com
Received: March 9, 2024
Revised: April 28, 2024
Accepted: May 13, 2024
Published online: June 26, 2024
Processing time: 100 Days and 21.7 Hours
Abstract
BACKGROUND

Parathyroid carcinoma (PC) is a difficult-to-diagnose rare disease with low incidence. Relatively accurate preoperative diagnosis is very important in choosing surgical methods and patient prognosis.

CASE SUMMARY

This study reported the clinical diagnosis and treatment of a rare patient with PC located in the thyroid gland and provided a case reference for the diagnosis and treatment of PC. A case of a 64-year-old male patient who presented to our hospital with systemic muscle and joint pain and palpitations is outlined. Subsequently, the patient was admitted to the Department of Nephrology for the treatment of “multiple myeloma nephropathy pending investigation”. The patient was diagnosed with “primary hyperparathyroidism and hypercalcemic crisis” using thyroid color ultrasound.

CONCLUSION

The intraoperative frozen section report considered the parathyroid tumor. Surgical tumor resection was promptly performed, and the diagnosis of PC was confirmed.

Keywords: Parathyroid carcinoma; Surgical resection; Fine needle aspiration; Intraoperative frozen section; Case report

Core Tip: Parathyroid carcinoma (PC) is a difficult-to-diagnose rare disease with low incidence. Relatively accurate preoperative diagnosis is very important in choosing surgical methods and patient prognosis. This study reported a rare patient with PC located in the thyroid gland. Combined with the results of color thyroid ultrasound and intraoperative frozen section, the primary disease of the patient can be confirmed. Accurate preoperative diagnosis is helpful for timely surgical resection of the tumor and improving the therapeutic effect.