High-grade serous carcinoma of the fallopian tube in a young woman with chromosomal 4q abnormality: A case report

Figure 1 Next-generation sequencing of the whole exome. A: Copy numbers in all chromosomes; B: Duplication in chromosome 4q13.3 from 73004016 to 73138249 could have possibly affected the ANKRD17 and COX18 genes; C: Deletion in 4q23q24 from 99214690 to 103455006 could have possibly affected the ADH1A, ADH1B, ADH1C, ADH6, ADH7, BANK1, C4orf54, CENPE, CISD2, DAPP1, DDIT4L, DNAJB14, EMCN, H2AZ1, LAMTOR3, MANBA, MTTP, NFKB1, PPP3CA, SLC39A8, SLC9B1, SLC9B2, TRMT10A, and UBE2D3 genes.

Figure 2 Serous tubal intraepithelial cancer and high-grade serous carcinoma. Scale bar = 200 μm. A: Serous tubal intraepithelial cancer; B: High-grade serous carcinoma. Scale bar = 100 μm.

Figure 3 Immunohistochemistry of P53 in high-grade serous carcinoma. Scale bar = 200 μm.