Immune cell signatures and causal association with irritable bowel syndrome: A mendelian randomization study

Figure 1 The forest plot presents the causal associations between irritable bowel syndrome and diverse immune cell phenotypes. Inverse variance weighting indicates Inverse variance weighting, and CI denotes the confidence interval. Trails: Immunological phenotypes; Methods: Inverse variance weighting; NSNP: Number of single nucleotide polymorphisms; PVAL: Statistical P value; OR (95%CI): Represents the odds ratio and its 95% confidence interval; FDR: False discovery rate.

Figure 2 The forest plot illustrates the causal relationships between immune cell traits and irritable bowel syndrome. Inverse variance weighting denotes inverse variance weighting, and CI indicates the confidence interval. Trails: Immunological phenotypes; Methods: Inverse variance weighting; NSNP: Number of single nucleotide polymorphisms; PVAL: Statistical P value; OR (95%CI): Represents the odds ratio and its 95% confidence interval; FDR: False discovery rate.

Figure 3 Funnel plot analysis for the association between CD28+ CD45RA- CD8dim absolute cell counts and irritable bowel syndrome. MR: Mendelian randomization.

Figure 4 Scatter plot depicting the relationship between CD28+ CD45RA- CD8dim absolute cell counts and irritable bowel syndrome. MR: Mendelian randomization; SNP: Single nucleotide polymorphism.