Giant juvenile fibroadenoma in a 14-year old Chinese female: A case report

Figure 1 Breast ultrasonography. A: Panoramic ultrasound imaging reveals the left breast with a large benign mass (long arrow); B: Punctate Doppler flow signals (short arrow) at the edge of the breast mass.

Figure 2 Pathological examination. A: Low magnification (10 × 10 times) shows a massive ductal epithelial hyperplasia (black arrow) surrounded by a comparatively homogeneous stromal component (green arrow). The interstitial cells in the local lesions are dense, and there is no mitotic phase or cell abnormality; B: Low magnification (10 × 20 times) shows the columnar cells with punctate protrusion in the mammary ducts (black arrow). The density of stromal cells increased without obvious heteromorphism, which was mainly manifested by the interlaced cluster arrangement of fibroblasts and myofibroblasts (green arrow), showing the peritubular type.

Figure 3 Macroscopic view of the removed lump. A: Excised specimen of a well-defined giant juvenile fibroadenoma with a well-circumscribed, smooth, and bosselated outer surface; B: The mucilaginous section is grayish yellow, lobulated, and medium hardness.