Envafolimab combined with chemotherapy in the treatment of combined small cell lung cancer: A case report

Figure 1 Chest computed tomography. A and F: A left lower lobe mass with atelectasis was observed; B-D and G-I: After 6 cycles of chemotherapy and immunotherapy, the mass in the left lower lobe gradually decreased in size with treatment; E and J: After 6 cycles of chemotherapy and immunotherapy, the mass in the left lower lobe nearly disappeared by the 6^th cycle.

Figure 2  Fiberoptic bronchoscopy revealed a mass protruding from the orifice of the left lower lung inlet, covered with a necrotic white coating and bloody secretions.

Figure 3 Bronchial mucosal biopsy showed a large amount of necrosis; some cells showed fat spindles, large cells, and nuclear staining, and some cells were small, round and oval with degeneration. Combined with immunohistochemistry, a diagnosis of neuroendocrine carcinoma and poorly differentiated carcinoma was made.