Intestinal complications in patients with Crohn’s disease in the Brazilian public healthcare system between 2011 and 2020

Figure 1 Patient attrition flowchart. CD: Crohn’s disease; CVT: Conventional therapy; SUS: Sistema Único de Saúde; TNF: Tumor necrosis factor; UC: Ulcerative colitis.

Figure 2 Annual rates of intestinal complications. A: The overall population with CD (n = 16809); B: CVT-only population (n = 12163); C: Anti-TNF therapy population (n = 4646). CD: Crohn’s disease; CVT: Conventional therapy; TNF: Tumor necrosis factor.

Figure 3 Kaplan–Meier curve depicting time to intestinal complications in the general population with Crohn’s disease (n = 16809) according to the type of intestinal complications (overall, associated disease, hospitalization-related, or procedure-related).

Figure 4 Kaplan–Meier curve depicting the time to intestinal complications in the general population with Crohn’s disease (n = 16809) and subgroups conventional therapy-only cohort (n = 12163) and anti-tumor necrosis factor-therapy cohort (n = 4646). CVT: Conventional therapy; TNF: Tumor necrosis factor.