Successful treatment of breast metastasis from primary transverse colon cancer: A case report

Figure 1 Imaging findings of the abdominal tumor and breast tumor. A: Abdominal computed tomography showed that the abdominal tumor measured 7.5 cm × 10.9 cm, with uneven density, and the boundary between the tumor and the surrounding tissues was unclear; B: Breast ultrasound clearly showed the breast tumor measuring 2.1 cm × 1.5 cm × 1.3 cm, with an unclear boundary and echo heterogenicity. Color Doppler flow imaging showed short rod blood flow signal.

Figure 2 Immunohistochemical and histological features of the primary colon cancer and breast metastasis from colon cancer. A-C: Immunohistochemical staining showed expression of caudal-related homeobox transcription factor 2 (A), mucin-2 (B), and villin (C) in colon cancer; D and E: Hematoxylin and eosin (H&E) staining showed intracellular mucus in colon cancer (D, 40 ×; E, 200 ×); F: H&E staining showed breast metastasis from colon cancer (40 ×); G: H&E staining showed adenocarcinoma cells in the breast metastasis (200 ×); H: Immunohistochemical staining showed negative expression of GATA binding protein-3 in breast metastasis from colon cancer.

Figure 3 Changes in serum levels of carcinoembryonic antigen, carbohydrate antigen 72-4, and carbohydrate antigen 125. A: Carbohydrate antigen (CA) 125 (0-35 U/mL); B: CA72-4 (0-6.9 U/mL); C: Carcinoembryonic antigen (0-10 ng/mL). CA: Carbohydrate antigen; CEA: Carcinoembryonic antigen.