Total removal of a large esophageal schwannoma by submucosal tunneling endoscopic resection: A case report and review of literature

Figure 1 Plain and contrast-enhanced chest computed tomography. A: Coronal view of chest computed tomography (CT) showed that the tumor in the middle and upper esophagus had clear boundaries and homogeneous density; B: Sagittal view of the CT scan revealed the mass was located in the posterior mediastinum, and the upper and lower diameters were larger than the anterior and posterior diameters; C and D: Axial view of CT demonstrated the tumor presented homogeneous enhancement.

Figure 2 Steps of submucosal tunneling endoscopic resection. A: Upper gastrointestinal endoscopy showing smooth elevated lesion; B: Submucosal tumor; C: Peeling the lesion; D: Closing the mucosal incision site with clips.

Figure 3 Histology and immunohistochemistry of the tumor. A: Histopathologic findings revealed spindle-shaped cells in a fasciculated and disarrayed architecture, and no pathologic mitosis was observed (hematoxylin and eosin staining; (magnification, × 400); B: The mitotic activity rate was < 5% on Ki-67 staining (magnification, × 80); C: Immunochemical analysis revealed no staining with CD117 (magnification, × 80); D: Immunohistochemical examination revealed S-100 protein positivity (magnification, × 200).