Age-adjusted NT-proBNP could help in the early identification and follow-up of children at risk for severe multisystem inflammatory syndrome associated with COVID-19 (MIS-C)

Figure 1 Bar (left panel) and box-plot (right panel) diagrams showing the dynamics of different cardiac measurements. A: Ross modified score; B: High Sensitivity-Troponin I; C: N-terminal pro-brain natriuretic peptide; D: Left ventricular ejection fraction; obtained at 4 different time points in this study. NT-proBNP: N-terminal pro-brain natriuretic peptide; LVEF: Left ventricular ejection fraction.

Figure 2 Box-plot diagrams showing the comparison of left ventricular ejection fraction (left panel) and N-terminal pro-brain natriuretic peptide (right panel) between groups of multisystem inflammatory syndrome in children severity. PICU: Pediatric intensive care unit.

Figure 3 Scatter-plot diagrams. A: The association between N-terminal pro-brain natriuretic peptide and Ross modified score; B: High Sensitivity-Troponin I; C: Left ventricular ejection fraction.