Case Report
Copyright ©The Author(s) 2022.
World J Clin Cases. Oct 6, 2022; 10(28): 10366-10374
Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10366
Figure 1
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Figure 1 Physical examination (March 16, 2020) revealed hyperpigmentation and nail atrophy in the patients. A: Lips and skin; B: Skin and fingernails; C: Skin and toenails.
Figure 2
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Figure 2 Diffuse polypoid protrusion and congested surface mucosa and lower gastrointestinal endoscopy (March 30, 2020). Congestion of the whole colonic mucosa with edema, erosion, granular bulge, and partially nodular characteristics. A: Gastric antrum; B: Gastric body; C: Duodenum; D: Ileocecum; E: Ascending colon; F: Transverse colon.
Figure 3
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Figure 3 Histopathological examination of lesions in the colon visualized by hematoxylin-eosin staining (March 30, 2020). The disease tests of polyps revealed hyperplastic and juvenile polyps. A: Terminal ileum; B: Transverse colon; C: Ectum. (A-C: Hematoxylin-eosin staining × 100).
Figure 4
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Figure 4 Physical examination identified that the pigmentation had subsided, and the nail growth was nearly normal. A: Lips and skin (July 1, 2020); B: Skin and fingernails (July 1, 2020); C: Lips and skin (October 28, 2020); D: Fingernails (October 28, 2020).
Figure 5
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Figure 5 Upper gastrointestinal endoscopy. The mucosal polypoid protrusion was significantly improved (July 1, 2020). Presence of mucosal congestion and edema (October 28, 2020). A: Gastric antrum (July 1, 2020); B: Gastric body (July 1, 2020); C: Duodenum (July 1, 2020); D: Gastric antrum (October 28, 2020); E: Gastric body (October 28, 2020); F: Duodenum (October 28, 2020).
Figure 6
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Figure 6 Lower gastrointestinal endoscopy. The mucosal polypoid protrusion was significantly improved (July 1, 2020). More than 10 polyps of different sizes and shapes with a diameter of about 0.3-1.0 cm can be seen throughout the large intestine (October 28, 2020 and June 8, 2021). A: Ileocecum (July 1, 2020); B: Ascending colon (July 1, 2020); C: Transverse colon (July 1, 2020); D-F: October 28, 2020; G-I: June 8, 2021; J: Hepatic flexure polyp (January 14, 2021); K: Descending colon polyps (January 14, 2021); L: Sigmoid colon polyps (January 14, 2021).