Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2022; 10(28): 10366-10374
Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10366
Thalidomide combined with endoscopy in the treatment of Cronkhite-Canada syndrome: A case report
Jia-Mei Rong, Meng-Lin Shi, Jun-Kun Niu, Juan Luo, Ying-Lei Miao
Jia-Mei Rong, Meng-Lin Shi, Jun-Kun Niu, Juan Luo, Ying-Lei Miao, Department of Gastroenterology, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan Province, China
Author contributions: Rong JM and Shi ML contributed to manuscript writing and editing, and data collection; Niu JK and Luo J helped revise the manuscript; Miao YL reviewed and revised the entire manuscript; all authors read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 82170550.
Informed consent statement: A written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: The authors have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying-Lei Miao, PhD, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road, Kunming 650032, Yunnan Province, China. miaoyinglei@kmmu.edu.cn
Received: July 9, 2022
Peer-review started: July 9, 2022
First decision: August 1, 2022
Revised: August 5, 2022
Accepted: August 24, 2022
Article in press: August 24, 2022
Published online: October 6, 2022
Processing time: 79 Days and 21 Hours
Core Tip

Core Tip: Cronkhite-Canada syndrome (CCS) is a rare non-hereditary disease with a poor prognosis and a mortality rate of up to 55%. Currently, there is no standard treatment for CCS. The symptoms of the patient in this case were significantly improved after treatment with thalidomide combined with endoscopy, and they were followed up for 2 years. No obvious adverse reactions were observed. Thalidomide may be a new potential therapeutic drug for CCS, and we will continue to follow up to determine its long-term efficacy.