Coexistent Kaposi sarcoma and post-transplant lymphoproliferative disorder in the same lymph nodes after pediatric liver transplantation: A case report

Figure 1 Histopathological changes observed in this case. A: Lymph nodes exhibited multifocal hyperplasia of spindle cells around small blood vessels, mainly beneath the capsule (arrows), and many lymphoid cells in the cortical and medullary regions of the lymph node (hematoxylin and eosin staining, × 40); B: Spindle cells exhibited minimal atypia (large arrow, upper left); heavy infiltration of plasma cells (small arrow, lower right) (hematoxylin and eosin staining, × 100).

Figure 2 Immunohistochemical features. A: Positive membrane staining for CD34 of spindle tumor cells (× 100); B: Positive nuclear staining for human herpesvirus-8 in parts of spindle tumor cells (× 200); C: Positive staining for CD138 of lymphoid cells (× 100); D: Positive staining for multiple myeloma 1 of lymphoid cells (× 100).

Figure 3 In situ hybridization. Epstein-Barr encoded RNA in situ hybridization revealed Epstein-Barr virus-positive lymphoid cells (× 200).