Diagnosis of an extremely rare case of malignant adenomyoepithelioma in pleomorphic adenoma: A case report

Figure 1 Breast ultrasound examination. A: The lump and the surrounding boundary are clear, and the echo is uneven; B: Disturbance of blood flow signal in some areas, Breast Imaging Reporting and Data System score: 4C; C: Nodular soft tissue shadow in the right breast area.

Figure 2 Pathological findings. A: A glandular tubular structure is seen in the lesion, which contains pale eosin secretions × 200 HE; B: The tumor and the surrounding area are unclear in some areas, showing invasive growth × 100 HE; C: The tumor cells were heterotypic, with a high ratio of cytoplasm to nuclei; multiple mitotic figures × 400 HE; D: p63 shows intact myoepithelial × 200 IHC; E: HMGA2 fragmentation probe: Count 100 cells, 1R1G1F accounted for 1%, 1R1F accounted for 1%; F: PLAG1 fragmentation probe: Count 100 cells, 1R1G1F accounted for 2%.