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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 6, 2021; 9(4): 886-897
Published online Feb 6, 2021. doi: 10.12998/wjcc.v9.i4.886
Published online Feb 6, 2021. doi: 10.12998/wjcc.v9.i4.886
Adult-onset Still's disease evolving with multiple organ failure and death: A case report and review of the literature
Zhong-Bin Han, Ju Wu, Department of Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Jing Liu, Tong Sun, Department of ICU, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
He-Ming Li, Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, China
Kai Guo, Department of Surgery, Second People's Hospital of Jinzhong City, Jinzhong 030600, Shanxin Province, China
Author contributions: Han ZB and Sun T were the patient’s managing physician, reviewed the literature, and contributed to manuscript drafting; Wu J, Liu J, and Guo K collected the patient’s past medical histories, reviewed the literature, and contributed to manuscript drafting; Li HM was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tong Sun, MAMS, Associate Professor, Director, Doctor, Department of ICU, Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Dalian 116001, Liaoning Province, China. 13704119600@163.com
Received: September 5, 2020
Peer-review started: September 5, 2020
First decision: November 20, 2020
Revised: November 28, 2020
Accepted: December 10, 2020
Article in press: December 10, 2020
Published online: February 6, 2021
Peer-review started: September 5, 2020
First decision: November 20, 2020
Revised: November 28, 2020
Accepted: December 10, 2020
Article in press: December 10, 2020
Published online: February 6, 2021
Core Tip
Core Tip: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disease, and the lack of disease-specific symptoms and laboratory markers hinders the diagnosis and assessment of its progression. More importantly, the treatment of AOSD remains largely empirical, with a lack of controlled clinical trials. Few cases of the disease with multiple complications have been reported. The present case highlights the characteristics of AOSD and severe complications and shares our experience in its diagnosis and treatment to provide experience for the effective recognition and treatment of this disease. The authors also note the link between the biopsychosocial model and autoimmune diseases.