Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2021; 9(36): 11220-11227
Published online Dec 26, 2021. doi: 10.12998/wjcc.v9.i36.11220
Published online Dec 26, 2021. doi: 10.12998/wjcc.v9.i36.11220
COVID-19 pandemic and exacerbation of ulcerative colitis
Toshikuni Suda, Yasumi Katayama, Masaya Tamano, Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Koshigaya 343-8555, Japan
Morio Takahashi, Department of Gastroenterology, Morio Clinic, Koshigaya 343-0808, Japan
Author contributions: Suda T recruited patients and drafted the manuscript; Takahashi M designed the study and analyzed data; Katayama Y revised the manuscript; Tamano M supervised the study.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Dokkyo Medical University Saitama Medical Center (approval No. 20100).
Informed consent statement: All patients provided informed consent to participate in this study and agreed to publication of the research results.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Toshikuni Suda, MD, PhD, Doctor, Instructor, Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-Koshigaya, Koshigaya-Shi, Saitama, Koshigaya 343-8555, Japan. toshikuni.suda@gmail.com
Received: June 7, 2021
Peer-review started: June 7, 2021
First decision: June 25, 2021
Revised: July 5, 2021
Accepted: November 15, 2021
Article in press: November 15, 2021
Published online: December 26, 2021
Processing time: 199 Days and 2.3 Hours
Peer-review started: June 7, 2021
First decision: June 25, 2021
Revised: July 5, 2021
Accepted: November 15, 2021
Article in press: November 15, 2021
Published online: December 26, 2021
Processing time: 199 Days and 2.3 Hours
Core Tip
Core Tip: Previous reports have suggested that physical and mental stress can exacerbate ulcerative colitis (UC). The coronavirus disease 2019 (COVID-19) pandemic caused anxiety and stress due to severe restrictions on economic and social activities. We demonstrated, for the first time, that the first wave of the COVID-19 pandemic induced UC exacerbations. Preventive treatments such as increased 5-ASA or local administration may be preferable in situations predicted to be stressful such as pandemics.