Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2021; 9(36): 11183-11192
Published online Dec 26, 2021. doi: 10.12998/wjcc.v9.i36.11183
Cognitive magnetic resonance imaging-ultrasound fusion transperineal targeted biopsy combined with randomized biopsy in detection of prostate cancer
Cheng Pang, Miao Wang, Hui-Min Hou, Jian-Yong Liu, Zhi-Peng Zhang, Xuan Wang, Ya-Qun Zhang, Chun-Mei Li, Wei Zhang, Jian-Ye Wang, Ming Liu
Cheng Pang, Miao Wang, Hui-Min Hou, Jian-Yong Liu, Zhi-Peng Zhang, Xuan Wang, Ya-Qun Zhang, Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
Miao Wang, Jian-Yong Liu, Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
Chun-Mei Li, Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, Beijing, China
Wei Zhang, Department of Pathology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, Beijing, China
Jian-Ye Wang, Ming Liu, Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China, China
Author contributions: Pang C and Wang M designed the study, acquired and analyzed the data, wrote the paper, and contributed equally to this article; Hou HM, Liu JY and Zhang ZP contributed to data analysis and interpretation; Wang X and Zhang YQ revised the paper; Li CM, Zhang W and Wang JY acquired and analyzed the data; Liu M designed the research, revised the paper and supervised the report; all authors made critical revisions related to the important intellectual content of the manuscript and provided the final approval of the version of the article to be published.
Supported by the Beijing Hospital Clinical Research 121 Project (BJ-2018-090 to Ming Liu).
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Beijing Hospital (2018BJYYEC-028-02).
Informed consent statement: Written informed consent was obtained from the patient or his/her guardians prior to the study.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming Liu, MD, Chief Doctor, Professor, Surgeon, Surgical Oncologist, Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Dahua Road, Dongcheng District, Beijing 100730, China. liumingbjh@126.com
Received: January 20, 2021
Peer-review started: January 20, 2021
First decision: September 28, 2021
Revised: October 15, 2021
Accepted: November 3, 2021
Article in press: November 3, 2021
Published online: December 26, 2021
Core Tip

Core Tip: Prostate biopsy remains the standard diagnostic modality before curative treatment. Cognitive magnetic resonance imaging (MRI)-ultrasound fusion biopsy is a more accessible and economical biopsy technique for small-sample institutions to realize imaging-guided targeted biopsy. In this study, we proposed a customized template and reported a feasible approach for cognitive MRI-ultrasound fusion biopsy with our single institutional experience. The results from this retrospective study revealed that a high yield of cancer, and that patients with higher prostate-specific antigen density and Prostate Imaging-Reporting and Data System scores are more likely to be diagnosed with prostate cancer under this biopsy strategy.