Guo HJ, Jiang F, Chen C, Shi JY, Zhao YW. Plasma brain natriuretic peptide, platelet parameters, and cardiopulmonary function in chronic obstructive pulmonary disease. World J Clin Cases 2021; 9(36): 11165-11172 [PMID: 35071547 DOI: 10.12998/wjcc.v9.i36.11165]
Corresponding Author of This Article
Feng Jiang, MM, Attending Doctor, Department of Cardiology, Affiliated Hospital of Nantong University, No. 20 Xisi Road, Nantong 226001, Jiangsu Province, China. jiangfengjf53@163.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hai-Jian Guo, Feng Jiang, Chu Chen, Jia-Yu Shi, Ya-Wen Zhao, Department of Cardiology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China
Author contributions: Guo HJ and Chen C coordinated and conducted most of the experiments and data analysis and participated in drafting the manuscript; Zhao YW participated in data analysis; Shi JY performed data analysis and revised the manuscript; Jiang F supervised the project and experimental design and provided financial support; Guo HJ wrote the main part of the paper; and all authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Affiliated Hospital of Nantong University.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No potential competing interests were reported by the authors.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
STROBE statement: The manuscript was checked according to the STROBE.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Feng Jiang, MM, Attending Doctor, Department of Cardiology, Affiliated Hospital of Nantong University, No. 20 Xisi Road, Nantong 226001, Jiangsu Province, China. jiangfengjf53@163.com
Received: September 14, 2021 Peer-review started: September 14, 2021 First decision: October 18, 2021 Revised: November 1, 2021 Accepted: November 18, 2021 Article in press: November 18, 2021 Published online: December 26, 2021 Processing time: 100 Days and 5.4 Hours
Core Tip
Core Tip: In this study, we estimated and compared the plasma brain natriuretic peptide (BNP) and platelet count parameters among different groups and subgroups. We found that plasma BNP and platelet parameters in patients with chronic obstructive pulmonary disease (COPD) and pulmonary heart disease clearly differed from those of the subjects in the COPD and healthy control groups. Moreover, with the increase in pulmonary arterial pressure and grading of heart function classification in the pulmonary heart disease group, plasma BNP and platelet-associated indices showed an apparent trend. Therefore, our study showed that plasma BNP and platelet parameters are correlated with the classification of pulmonary arterial pressure and cardiac function in patients with combined COPD and pulmonary heart disease, which indicate that these parameters have high relevance in reflecting the patients’ health condition and in guiding their clinical treatment.
