Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 11078-11084
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.11078
Double-mutant invasive mucinous adenocarcinoma of the lung in a 32-year-old male patient: A case report
Ting Wang
Ting Wang, Department of Respiratory Medicine, Xi’an People’s Hospital (The Fourth Xi’an Hospital), Xi’an 710049, Shannxi Province, China
Author contributions: Wang T is responsible for manuscript writing, data collection, and performing the analysis with constructive discussions.
Informed consent statement: Written consent to publish the clinical or possible personal information was obtained from the participant included in the study.
Conflict-of-interest statement: Dr. Wang has nothing to disclose.
CARE Checklist (2016) statement: The content of the article is consistent with CARE Checklist (2016) Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ting Wang, PhD, Doctor, Department of Respiratory Medicine, Xi’an People’s Hospital (The Fourth Xi’an Hospital), No. 21 Jiefang Road, Xincheng District, Xi’an 710049, Shannxi Province, China. hdwt.ok@163.com
Received: June 24, 2021
Peer-review started: June 24, 2021
First decision: July 26, 2021
Revised: July 27, 2021
Accepted: September 15, 2021
Article in press: September 15, 2021
Published online: December 16, 2021
Processing time: 168 Days and 22.1 Hours
Core Tip

Core tip: Invasive mucinous adenocarcinoma of the lung is a rare category of lung tumors, radiologically characterized by dense pneumonic consolidation, ground-glass opacity, crazy paving, and nodules. Early pleural effusion is uncommon in this malignancy. Molecularly, invasive mucinous adenocarcinoma has frequent Kirsten rat sarcoma viral oncogene mutations and a lower prevalence of epidermal growth factor receptor and anaplastic lymphoma kinase rearrangements. Here, a rare case of double-mutant invasive mucinous lung adenocarcinoma presenting as a massive malignant pleural effusion in a 32-year-old male patient was reported.