Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 11071-11077
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.11071
Signet ring cell carcinoma hidden beneath large pedunculated colorectal polyp: A case report
Jia-Ning Yan, Yong-Fu Shao, Guo-Liang Ye, Yong Ding
Jia-Ning Yan, Yong-Fu Shao, Guo-Liang Ye, Yong Ding, Department of Gastroenterology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo 315020, Zhejiang Province, China
Author contributions: Ye GL and Ding Y were the operators of the patient’s colonoscopy; Yan JN interpreted the findings, reviewed the literature and contributed to manuscript drafting; Shao YF was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by the National Natural Science Foundation of China, No. 81702367; and the Science and Technology Development Funds of Ningbo of China (Normal Program), No. 2020F028.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong Ding, PhD, Academic Fellow, Chief Doctor, Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Medical School of Ningbo University, No. 247 Renming Road, Ningbo 315020, Zhejiang Province, China. dingy135@126.com
Received: June 29, 2021
Peer-review started: June 29, 2021
First decision: July 26, 2021
Revised: July 28, 2021
Accepted: October 25, 2021
Article in press: October 25, 2021
Published online: December 16, 2021
Processing time: 163 Days and 15.9 Hours
Core Tip

Core Tip: Pedunculated polyp itself is considered to have a low degree of malignancy. Herein, we present a rare case of a large pedunculated polyp that contains signet ring cells and infiltrates the submucosal layer. This case highlights the malignancy of pedunculated polyps, and even if adenomas may be fragile, endoscopy doctors should still remove polyps as completely as possible and choose perpendicular sections through the stalk and base for fixation.