Meta-Analysis
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 10979-10993
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.10979
Percutaneous biliary stent combined with brachytherapy using 125I seeds for treatment of unresectable malignant obstructive jaundice: A meta-analysis
Wei-Yue Chen, Chun-Li Kong, Miao-Miao Meng, Wei-Qian Chen, Li-Yun Zheng, Jian-Ting Mao, Shi-Ji Fang, Li Chen, Gao-Feng Shu, Yang Yang, Qiao-You Weng, Min-Jiang Chen, Min Xu, Jian-Song Ji
Wei-Yue Chen, Chun-Li Kong, Miao-Miao Meng, Wei-Qian Chen, Li-Yun Zheng, Jian-Ting Mao, Shi-Ji Fang, Li Chen, Gao-Feng Shu, Yang Yang, Qiao-You Weng, Min-Jiang Chen, Min Xu, Jian-Song Ji, Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research/Department of Radiology, Lishui Hospital of Zhejiang University, Lishui 323000, Zhejiang Province, China
Author contributions: Chen WY, Kong CL, and Meng MM acquired, analyzed, and interpreted the data, and drafted the manuscript; Chen WQ, Zheng LY, Mao JT, and Fang SJ analyzed the data and drafted the manuscript; Chen L, Shu GF, and Yang Y interpreted the data and revised the manuscript; Ji JS, Xu M, Chen MJ, and Weng QY conceptualized and designed the study, and critically revised the manuscript; all authors approved the final manuscript.
Supported by the Medical Health Science and Technology Project of Zhejiang Provincial Health Commission, No. 2020KY1086 and No. 2020KY1087.
Conflict-of-interest statement: The authors deny any conflict of interest related to this manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Song Ji, MD, PhD, Chief Doctor, Surgical Oncologist, Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research/Department of Radiology, Lishui Hospital of Zhejiang University, No. 289 Kuocang Road, Liandu District, Lishui 323000, Zhejiang Province, China. jijiansong@zju.edu.cn
Received: June 24, 2021
Peer-review started: June 24, 2021
First decision: July 27, 2021
Revised: August 3, 2021
Accepted: November 2, 2021
Article in press: November 2, 2021
Published online: December 16, 2021
Processing time: 168 Days and 15.4 Hours
Core Tip

Core Tip: In recent years, the incidence of malignant obstructive jaundice (MOJ) in Asia has been 40 times higher than that in the Western world, which is a vital issue that requires significant attention. Irradiation stents using 125I seeds have been widely applied in the treatment of unresectable MOJ. However, more convincing evidence-based reviews of the efficacy and safety of 125I seed stents are needed. We used the latest data to further validate the superiority of 125I seed stents, providing strong evidence for clinicians to make correct decisions in clinical practice. Furthermore, we found that 125I seed stents resulted in equivalent complication and serum index outcomes as conventional stents, indicating that 125I seed stents are safe and well tolerated.