Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 10765-10780
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.10765
Application of vascular endothelial cells in stem cell medicine
Qing-Qing Liang, Lei Liu
Qing-Qing Liang, Lei Liu, State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Liang QQ contributed to the literature review, and drafting and writing this paper as the first author; Liu L contributed to the revision and editing of the manuscript; and both authors gave approval to the final version to be submitted.
Supported by the National Natural Science Foundation of China, No. 81670951.
Conflict-of-interest statement: There are no potential conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei Liu, MD, PhD, Professor, State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, 14, Section 3, Renminnan Road, Chengdu 610041, Sichuan Province, China. drliulei@163.com
Received: May 31, 2021
Peer-review started: May 31, 2021
First decision: June 23, 2021
Revised: July 2, 2021
Accepted: October 27, 2021
Article in press: October 27, 2021
Published online: December 16, 2021
Processing time: 192 Days and 21.7 Hours
Core Tip

Core Tip: Vascular endothelial cells (VECs) are involved in several physiological and pathological processes, including angiogenesis, control of blood pressure, and treatment-resistant diseases. Therefore, researchers have applied VECs in stem cell medicine and achieved beneficial results, demonstrating that these cells have a broad potential for application in many fields. This review discusses the functions, applications, and challenges of VECs.