Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2021; 9(34): 10652-10658
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10652
Histology transformation-mediated pathological atypism in small-cell lung cancer within the presence of chemotherapy: A case report
Qing Ju, Ying-Tong Wu, Yong Zhang, Wen-Hui Yang, Cheng-Lei Zhao, Jian Zhang
Qing Ju, Ying-Tong Wu, Yong Zhang, Wen-Hui Yang, Jian Zhang, Department of Pulmonary and Critical Care Medicine, Xijing Hospital, Xi'an 710000, Shaanxi Province, China
Cheng-Lei Zhao, Department of Dermatology, Southwest Hospital, Chongqing 404100, China
Author contributions: Ju Q, Zhang Y and Zhang J contributed to the conceptualization; Ju Q, Wu YT and Zhao CL collected the information; Ju Q, Zhang Y, Wu YT and Yang WH wrote the original draft; Wu YT, Zhang Y and Zhang J reviewed and edited the manuscript.
Informed consent statement: Informed written consent was obtained from the patient to publish this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicting interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Jian Zhang, PhD, Doctor, Professor, Department of Pulmonary and Critical Care Medicine, Xijing Hospital, No. 127 Changle West Road, Xi'an 710000, Shaanxi Province, China.
Received: February 9, 2021
Peer-review started: February 9, 2021
First decision: April 25, 2021
Revised: May 27, 2021
Accepted: October 20, 2021
Article in press: October 20, 2021
Published online: December 6, 2021
Core Tip

Core Tip: In this report, we present a male patient with a diagnosis of small-cell lung cancer (SCLC) who developed metastatic adenocarcinoma, a subtype of non-SCLC, after standard chemotherapy regimens. He has survived for 90 mo since the first diagnosis, which is longer than expected.