Retrospective Cohort Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2021; 9(31): 9406-9416
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9406
Establishment of a risk assessment score for deep vein thrombosis after artificial liver support system treatment
Yun Ye, Xiang Li, Li Zhu, Cong Yang, You-Wen Tan
Yun Ye, Xiang Li, Li Zhu, Cong Yang, You-Wen Tan, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212000, Jiangsu Province, China
Author contributions: Ye Y and Li X contributed equally to this manuscript; Tan YW and Ye Y designed the research; Zhu L and Yang C collected and analyzed the data, and drafted the manuscript; Tan YW, Ye Y and Li X wrote and revised the manuscript; all authors have read and approved the final version to be published.
Supported by China Public Health Alliance, No. GWLM202031.
Institutional review board statement: This study was approved by The Third Hospital of Zhenjiang Affiliated Jiangsu University.
Informed consent statement: Informed consent for this study was not required as the clinical data were anonymous.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: You-Wen Tan, MD, Chief Doctor, Professor, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, No. 300 Danjiamen, Runzhou District, Zhenjiang 212000, Jiangsu Province, China. tyw915@sina.com
Received: May 18, 2021
Peer-review started: May 18, 2021
First decision: June 12, 2021
Revised: June 13, 2021
Accepted: September 23, 2021
Article in press: September 23, 2021
Published online: November 6, 2021
Core Tip

Core Tip: The risk factors for deep vein thrombosis (DVT) after the use of an artificial liver support system (ALSS) and a risk assessment score were established. A total of 232 patients with liver failure treated with ALSS were enrolled in the first stage, including 12 with lower limb DVT. Logistic regression analysis showed that age, successful catheterization time, activity status (strict bed rest), and D-dimer level (≥ 500 ng/mL) were independent risk factors for DVT. In the risk assessment scoring system validation group, when the cutoff value of risk assessment was 3, the specificity and sensitivity of the risk assessment score were 88.9% and 85.7%, respectively.