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World J Clin Cases. Nov 6, 2021; 9(31): 9350-9367
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9350
Major depressive disorder: Validated treatments and future challenges
Rabie Karrouri, Zakaria Hammani, Roukaya Benjelloun, Yassine Otheman
Rabie Karrouri, Zakaria Hammani, Yassine Otheman, Department of Psychiatry, Moulay Ismaïl Military Hospital, Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, Fez 30070, Morocco
Roukaya Benjelloun, Department of Psychiatry, Faculty of Medicine, Mohammed VI University of Health Sciences, Casablanca 20000, Morocco
Author contributions: Karrouri R the main author, worked on the antidepressant chapter and coordinated all the work; Hammani Z, worked on the somatic treatment chapter; Otheman Y worked on the psychotherapy chapter, he also reviewed the data, and the references; Benjelloun R, participated in the development of the plan, and in the review of data, she revised and corrected the language quality of the article.
Conflict-of-interest statement: All authors declare that they have no conflict of interest related to this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yassine Otheman, MD, Associate Professor, Chief Doctor, Department of Psychiatry, Moulay Ismaïl Military Hospital, Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, 1893, Km 2.2 road of Sidi Hrazem, Fez 30070, Morocco. yassine.othemane@usmba.ac.ma
Received: March 31, 2021
Peer-review started: March 31, 2021
First decision: June 5, 2021
Revised: July 2, 2021
Accepted: October 11, 2021
Article in press: October 11, 2021
Published online: November 6, 2021
Processing time: 211 Days and 13.9 Hours
Core Tip

Core Tip: Depression is a persistent public health problem for which treatments must be codified and simplified to enhance current practice. Several therapies have been suggested worldwide, with varying levels of validity. This article explores effective and valid therapies for treating depression by addressing current and future research topics for different treatment categories.