Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2021; 9(28): 8295-8311
Published online Oct 6, 2021. doi: 10.12998/wjcc.v9.i28.8295
Nutrition, nutritional deficiencies, and schizophrenia: An association worthy of constant reassessment
Olakunle James Onaolapo, Adejoke Yetunde Onaolapo
Olakunle James Onaolapo, Behavioural Neuroscience/Neuropharmacology Unit, Department of Pharmacology, Ladoke Akintola University of Technology, Osun State 234, Nigeria
Adejoke Yetunde Onaolapo, Department of Anatomy, Ladoke Akintola University of Technology, Osun State 234, Nigeria
Author contributions: Both authors contributed equally to the writing of this manuscript.
Conflict-of-interest statement: The authors declare that there is no any conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Adejoke Yetunde Onaolapo, MBBS, MSc, PhD, Senior Lecturer, Department of Anatomy, Ladoke Akintola University of Technology, Ogbomoso, Osun State 234, Nigeria.
Received: February 28, 2021
Peer-review started: February 28, 2021
First decision: April 20, 2021
Revised: May 4, 2021
Accepted: August 10, 2021
Article in press: August 10, 2021
Published online: October 6, 2021
Core Tip

Core Tip: Schizophrenia is a mental health disorder with a significant socioeconomic burden and a complex pathophysiology. As the relationships that potentially link nutrition to the expression of symptoms and the progression of schizophrenia are becoming more apparent, the role of nutrition in schizophrenia management is becoming more important than previously thought. However, despite our current knowledge of the possible links between nutrition and schizophrenia, and some tentative pathways for this relationship, the larger challenge remains how to get to the point where precision dietary manipulation becomes a widely-accepted approach to schizophrenia prevention and a day-to-day management strategy.