Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2021; 9(25): 7551-7557
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7551
Hemorrhagic transformation after acute ischemic stroke caused by polycythemia vera: Report of two case
Ya-Yun Cao, Jie Cao, Zhua-Jin Bi, Sha-Bei Xu, Chen-Chen Liu
Ya-Yun Cao, Jie Cao, Zhua-Jin Bi, Sha-Bei Xu, Chen-Chen Liu, Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Ya-Yun Cao, Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan 430000, Hubei Province, China
Author contributions: Cao YY acquired the data and drafted the manuscript; Cao J acquired and analyzed the data; Bi ZJ analyzed and interpreted the imaging findings; Xu SB helped revise the manuscript; Liu CC designed the study and revised the manuscript; all authors have read and approved the manuscript.
Informed consent statement: Writtern informed consent was obtained from the patients for publication of this case report.
Conflict-of-interest statement: The authors declare no conflict of interest for this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chen-Chen Liu, MD, Doctor, Lecturer, Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430000, Hubei Province, China. liuchenchen8807@126.com
Received: February 28, 2021
Peer-review started: February 28, 2021
First decision: July 5, 2021
Revised: July 12, 2021
Accepted: July 19, 2021
Article in press: July 19, 2021
Published online: September 6, 2021
Processing time: 183 Days and 10.7 Hours
Core Tip

Core Tip: Polycythemia vera (PV) is a rare, myeloproliferative disorder. Ischemic stroke is the most frequent neurologic manifestation of PV. However, hemorrhagic transformation after acute ischemic stroke caused by PV has not been previously reported. Here, we present two patients with PV who developed hemorrhagic transformation after sustaining an acute ischemic stroke. Antiplatelet drugs did not lead to poor long-term outcomes in our patients.