Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2021; 9(24): 7085-7091
Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.7085
Tuberous sclerosis complex-lymphangioleiomyomatosis involving several visceral organs: A case report
Hong-Bin Chen, Xiao-Hong Xu, Cai-Gui Yu, Meng-Ting Wan, Chuang-Li Feng, Zhi-Yu Zhao, Dan-E Mei, Jin-Ling Chen
Hong-Bin Chen, Department of Pulmonary and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Xiao-Hong Xu, Department of Pulmonary and Critical Care Medicine, People's Hospital of Hanchuan, Hanchuan 431600, Hubei Province, China
Cai-Gui Yu, Meng-Ting Wan, Chuang-Li Feng, Zhi-Yu Zhao, Dan-E Mei, Jin-Ling Chen, Department of Echocardiography, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Author contributions: Chen HB and Xu XH designed the report; Chen JL collected the patient’s clinical data; Yu CG, Wan MT, Feng CL, Zhao ZY, and Mei DE analyzed the data and wrote the paper; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Ling Chen, MD, Chief Doctor, Department of Echocardiography, Renmin Hospital of Wuhan University, No. 238 Jiefang Road, Wuchang District, Wuhan 430060, Hubei Province, China. 77810848@qq.com
Received: April 29, 2021
Peer-review started: April 29, 2021
First decision: May 23, 2021
Revised: May 30, 2021
Accepted: July 2, 2021
Article in press: July 2, 2021
Published online: August 26, 2021
Core Tip

Core Tip: Lymphangioleiomyomatosis is a rare cystic lung disease that can be associated with tuberous sclerosis complex (TSC). The disorder of TSC has a variable expression and there is great phenotypic variability. A 32-year-old Chinese woman with a history of multiple renal angioleiomyolipoma since the age of 14 was diagnosed with TSC-lymphangioleiomyomatosis by high-resolution computed tomography, conventional and contrast ultrasonography, pathology through thoracoscopic lung biopsy, and high-throughput genome sequencing of peripheral blood DNA.