Case Control Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2021; 9(24): 6987-6998
Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.6987
Textural differences based on apparent diffusion coefficient maps for discriminating pT3 subclasses of rectal adenocarcinoma
Zhi-Hua Lu, Kai-Jian Xia, Heng Jiang, Jian-Long Jiang, Mei Wu
Zhi-Hua Lu, Heng Jiang, Department of Radiology, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People's Hospital, Changshu 215500, Jiangsu Province, China
Kai-Jian Xia, Department of Information, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People's Hospital, Changshu 215500, Jiangsu Province, China
Jian-Long Jiang, Department of Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People's Hospital, Changshu 215500, Jiangsu Province, China
Mei Wu, Department of Pathology, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People's Hospital, Changshu 215500, Jiangsu Province, China
Author contributions: Lu ZH conceived and coordinated the study, designed, performed, and analyzed the experiments, and wrote the paper; Xia KJ, Jiang H, Jiang JL, and Wu M carried out the data collection and analysis, and revised the paper; all authors reviewed the results and approved the final version of the manuscript.
Supported by Jiangsu Provincial Medical Youth Talent, No. QNRC2016212; Suzhou Clinical Special Disease Diagnosis and Treatment Program, No. LCZX201823; Suzhou GuSu Medical Talent Project, No. GSWS2019077; The Science and Technology Bureau of Changshu, No. CS201624 (to Lu ZH); and Jiangsu Committee of Health, No. H2018071 (to Xia KJ).
Institutional review board statement: This case-control study was approved by the Institutional Review Board of the Changshu Hospital Affiliated to Soochow University (2018 Ethics Audit (Declaration) Batch No. 3).
Informed consent statement: The requirement for individual informed consent was waived because of the retrospective design of the study.
Conflict-of-interest statement: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Hua Lu, MD, Doctor, Department of Radiology, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People's Hospital, No. 1 Shuyuan Street, Changshu 215500, Jiangsu Province, China. luzhihua79@163.com
Received: January 1, 2021
Peer-review started: January 1, 2021
First decision: January 24, 2021
Revised: March 1, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: August 26, 2021
Core Tip

Core Tip: Texture features derived from apparent diffusion coefficient maps might potentially differentiate pT3a rectal adenocarcinomas from pT3b-c tumors.