Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2021; 9(17): 4279-4284
Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4279
Stevens-Johnson syndrome and concurrent hand foot syndrome during treatment with capecitabine: A case report
Ha Rim Ahn, Sang-Kyung Lee, Hyun Jo Youn, Seok-Kweon Yun, Il-Jae Lee
Ha Rim Ahn, Hyun Jo Youn, Division of Breast and Thyroid Surgery, Department of Surgery, Jeonbuk National University, Jeonju 54907, South Korea
Ha Rim Ahn, Hyun Jo Youn, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju 54907, South Korea
Sang-Kyung Lee, Seok-Kweon Yun, Il-Jae Lee, Department of Dermatology, Jeonbuk National University Medical School, Jeonju 54907, South Korea
Author contributions: Ahn HR and Lee SK performed the case report and wrote the manuscript; Lee IJ, Ahn HR, edited the manuscript; Yun SK, Youn HJ supervised the work and edited the manuscript; all authors have read and approve the final manuscript.
Informed consent statement: This study was approved and reviewed by our Institutional Review Board.
Conflict-of-interest statement: The authors have no potential conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyun Jo Youn, MD, PhD, Chief Doctor, Surgeon, Division of Breast and Thyroid Surgery, Department of Surgery, Jeonbuk National University, 20 Gunji-ro, Jeonju 54907, South Korea. yhj0903@jbnu.ac.kr
Received: January 15, 2021
Peer-review started: January 15, 2021
First decision: February 11, 2021
Revised: February 15, 2021
Accepted: April 20, 2021
Article in press: April 20, 2021
Published online: June 16, 2021
Processing time: 131 Days and 7.1 Hours
Core Tip

Core Tip: Hand-foot syndrome (HFS) is a relatively well-known side effect of capecitabine treatment, although Stevens-Johnson syndrome (SJS) is not generally associated with capecitabine treatment. We report a case involving concurrent HFS and SJS. These side effects may decrease the patient's quality of life and delay chemotherapy for their primary disease. Therefore, clinicians should be aware of SJS as a rare side effect of capecitabine treatment and consider a multidisciplinary approach to treating this complication if necessary.