Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2021; 9(15): 3787-3795
Published online May 26, 2021. doi: 10.12998/wjcc.v9.i15.3787
Published online May 26, 2021. doi: 10.12998/wjcc.v9.i15.3787
Bilateral cerebral infarction in diabetic ketoacidosis and bilateral internal carotid artery occlusion: A case report and review of literature
Yi-Chung Chen, Su-Ju Tsai, Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital, Taichung 40201, Taiwan
Author contributions: Chen YC is the first author and wrote the case report and completed the literature review; Tsai SJ performed the final editing and prepared the paper for approval by the authors; all authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from legal representative.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Su-Ju Tsai, MD, MS, Associate Professor, Director, Department of Physical Medicine and Rehabilitation, Chung Shan Medical University; Director, Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital, No. 110 Sec.1, Jianguo N. Rd., Taichung 40201, Taiwan. sujutsai@gmail.com
Received: January 30, 2021
Peer-review started: January 30, 2021
First decision: February 25, 2021
Revised: March 2, 2021
Accepted: March 29, 2021
Article in press: March 29, 2021
Published online: May 26, 2021
Peer-review started: January 30, 2021
First decision: February 25, 2021
Revised: March 2, 2021
Accepted: March 29, 2021
Article in press: March 29, 2021
Published online: May 26, 2021
Core Tip
Core Tip: Diabetic ketoacidosis (DKA) causes vascular endothelial injury, systemic inflammation, vasoconstriction, abnormal coagulation cascade, increased platelet aggregation, and increased blood viscosity, all of which are associated with cerebral infarction. Bilateral internal carotid artery occlusion (BICAO) is a rare condition that can give rise to devastating ischemic strokes. DKA acts as an additional risk factor for ischemic stroke in a high-risk patient with BICAO, hypertension, hyperlipidemia, and type 1 diabetes mellitus.