Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2021; 9(15): 3704-3710
Published online May 26, 2021. doi: 10.12998/wjcc.v9.i15.3704
Malignant giant cell tumor in the left upper arm soft tissue of an adolescent: A case report
Wen-Peng Huang, Li-Na Zhu, Rui Li, Li-Ming Li, Jian-Bo Gao
Wen-Peng Huang, Li-Na Zhu, Rui Li, Li-Ming Li, Jian-Bo Gao, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Author contributions: Gao JB was the principal investigator and takes primary responsibility for the manuscript; Huang WP and Zhu LN analyzed and interpreted the patient data and wrote the manuscript draft, which was amended by Gao JB; All authors read and approved the final version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Bo Gao, MD, Professor, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou 450052, Henan Province, China. jianbogaochina@163.com
Received: January 7, 2021
Peer-review started: January 7, 2021
First decision: January 24, 2021
Revised: January 25, 2021
Accepted: March 12, 2021
Article in press: March 12, 2021
Published online: May 26, 2021
Core Tip

Core Tip: Giant cell tumor of soft tissue (GCT-ST) is a rare primary soft tissue tumor that sometimes leads to local recurrence, but rarely to distant metastasis. In this case, the tumor exhibited strip-like calcifications, and the mass destroyed the cortical bone and invaded the bone marrow cavity. Magnetic resonance imaging was performed to establish the extent of the mass. We found multiple small nodules beneath the pleura of both lungs, which we considered as metastases. Development of an aggressive GCT-ST after adolescent trauma is rare. GCT-ST should be considered when interpreting limb masses that involve calcification and bone destruction.